Is NAD IV worth it? For some people in Tulsa, yes. For plenty of others we tell them no and we mean it. NAD+ 500mg is $399. A session can run for hours, and the human research is thinner than the marketing around it. If you're chasing one good afternoon, spend the money elsewhere. If you're in for the long haul and will come back monthly, the math shifts.
We list our sources at the bottom so you can check us.
Your body builds NAD out of a B vitamin you already eat. The NIH Office of Dietary Supplements describes niacin from food being converted into its main metabolically active form, the coenzyme nicotinamide adenine dinucleotide (NAD), and it says what that coenzyme spends its day doing: NAD is primarily involved in catabolic reactions that transfer the potential energy locked in what you ate. MedlinePlus puts the same vitamin in one line. Niacin helps the digestive system, skin, and nerves to function.
So the molecule is real and it does real work in you. The B3 you buy as a pill is a different animal, though. That same NIH sheet notes that Thirty to 50 mg or more nicotinic acid typically causes flushing, which a bag of NAD does not do. People talk about the two as if they were interchangeable. They aren't.
Most pages selling this won't print the next part. A 2025 review in Nature Metabolism walked through the clinical evidence and found the founding premise only lightly supported in people, reporting that an age related fall in NAD levels has been consistently observed only in a limited number of studies. On the supplements built on that premise, the same review doesn't soften anything: human clinical trials have shown limited efficacy. On the wider picture it adds that the published body of data on NAD+ dynamics in human tissues remains sparse.
Read that closely, because it cuts in both directions. The trials behind it mostly measured precursors people swallowed rather than NAD running straight into a vein, so the finding is not aimed at what we hang on your arm. Nobody has published the work that would show an IV changes the conclusion either, which is the part the sales copy skips. So we land on not knowing. That isn't the same as saying it works, and it isn't the same as saying it doesn't. We won't tell you the evidence backs this up, and we won't act as though somebody has ruled it out, because nobody has. A nurse who pretends otherwise in either direction is selling you something. Here's what we can do instead. Tell you the price before anyone packs the car, run the bag safely, and let you decide whether that unknown is worth $399.
NAD+ 500mg is $399, all in, the full dose in saline with nothing else riding along. Figure 1 to 3 hours, because NAD gets run slowly on purpose. Our page says the nurse runs it at the pace your body is comfortable with, which is also why she sits with you start to finish instead of hanging a bag and leaving. A physician reviews the order before anything gets opened. Injections you add while it runs are $25 each.
Cellular Rewind is also $399 and holds the same amount of NAD, with a B complex, vitamin C and glutathione along for the ride. Same money, fuller bag, which is why we steer most first timers to Rewind and say so right on the 500mg page. Some people take the 500 anyway, wanting the dose by itself with nothing else to weigh. Either way you are out $399 and most of an afternoon.
Everyone on our service list pays the menu number, whether the nurse drives into Tulsa or out to Claremore. Sand Springs and Sapulpa add a flat $25 for the trip.
A fair number of these conversations end with a smaller bag or nothing at all. If what you want is fluids after a brutal week, Simply Hydrate is $99 and that's the whole visit. If you're run down from something going around, that's its own question and we went at it separately in whether a vitamin IV helps when you're sick. If you're hoping an infusion sorts out something a doctor is already following, that belongs with whoever holds your chart. And if $399 would sting this month, it'll still be $399 in November.
The membership only earns its keep once you've decided you're in. The NAD+ Longevity path runs $349 a month for one NAD infusion a month, $50 lower than $399 at the door, on a three month minimum. Still weighing whether NAD belongs in your life? Pay the $399 once and find out, then decide. The rest of the menu is there either way.
This page is general education, not medical advice about your body, and no infusion replaces the doctor who knows your history. Ask them first if you take prescription medication or you have something ongoing under watch.
Nature Metabolism: NAD precursor supplementation in human ageing, peer-reviewed, a 2025 review of the clinical evidence
NIH Office of Dietary Supplements: Niacin, government health agency, its fact sheet for health professionals
MedlinePlus: Niacin, government health agency, its encyclopedia entry on the vitamin, reviewed January 2025
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